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Article

Molecular differentiation between osteophytic and articular cartilage--clues for a transient and permanent chondrocyte phenotype.

Osteoarthritis and cartilage - 1 Feb 2012

Gelse K, Ekici A B, Cipa F, Swoboda B, Carl H D, Olk A, Hennig F F, Klinger P

Abstract excerpt

OBJECTIVE: To identify the molecular differences between the transient and permanent chondrocyte phenotype in osteophytic and articular cartilage. METHODS: Total RNA was isolated from the cartilaginous layer of osteophytes and from intact articular cartilage from knee joints of 15 adult human donors and subjected to cDNA microarray analysis. The differential expression of relevant genes between these two...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22209871
DOI: 10.1016/j.joca.2011.12.004

Genes

BGLAP
GREM1
FRZB
HAS1
PTHLH
RUNX2
SOST
SOX9
STC2
WNT1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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