Article
Cystic fibrosis mutations in North American populations of French ancestry: analysis of Quebec French-Canadian and Louisiana Acadian families.
American journal of human genetics - 1 Oct 1990
Rozen R, Schwartz R H, Hilman B C, Stanislovitis P, Horn G T, Klinger K, Daigneault J, De Braekeleer M, Kerem B, Tsui L
Abstract excerpt
A 3-bp deletion (delta F508) in the cystic fibrosis (CF) gene is the mutation on the majority of CF chromosomes. We studied 112 CF families from North American populations of French ancestry: French-Canadian families referred from hospitals in three cities in Quebec and from the Saguenay-Lac St. Jean region of northeastern Quebec and Acadian families living in Louisiana. delta F508 was present on 71%, 55%, and...
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