Article
Analysis of four diverse population groups indicates that a subset of cystic fibrosis mutations occur in common among Caucasians.
American journal of human genetics - 1 Jun 1992
Cutting G R, Curristin S M, Nash E, Rosenstein B J, Lerer I, Abeliovich D, Hill A, Graham C
Abstract excerpt
To determine the nature and frequency of non-delta F508 cystic fibrosis (CF) mutations among diverse populations, we have sequenced exons 9-12 and 19-23 of the CF transmembrane conductance regulator (CFTR) gene from 128 CF chromosomes (39 U.S. Caucasian, 27 African-American, 42 Northern Irish, an...
Topics
- Amino Acid Sequence
- Base Sequence
- Black People
- Chromosome Deletion
- Cystic Fibrosis
- Cystic Fibrosis Transmembrane Conductance Regulator
- DNA
- Ethnicity
- Exons
- Frameshift Mutation
- Humans
- Lymphocytes
- Membrane Proteins
- Molecular Sequence Data
- Mutation