Article
Metabolic diversity of progressive kidney disease in 325 patients with type 1 diabetes (the FinnDiane Study).
Journal of proteome research - 2 Mar 2012
Mäkinen Ville-Petteri, Tynkkynen Tuulia, Soininen Pasi, Peltola Tomi, Kangas Antti J, Forsblom Carol, Thorn Lena M, Kaski Kimmo, Laatikainen Reino, Ala-Korpela Mika, Groop Per-Henrik
Abstract excerpt
Type 1 diabetic patients with varying severity of kidney disease were investigated to create multimetabolite models of the disease process. Urinary albumin excretion rate was measured for 3358 patients with type 1 diabetes. Prospective records were available for 1051 patients, of whom 163 showed progression of albuminuria (8.3-year follow-up), and 162 were selected as stable controls. At baseline, serum lipids,...
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