Article
Comparative analysis of nuclear transfer embryo-derived mouse embryonic stem cells. Part II: gene regulation.
Cellular reprogramming - 1 Feb 2012
Kobolak Julianna, Horsch Marion, Geissler Sandra, Mamo Solomon, Beckers Johannes, Dinnyes Andras
Abstract excerpt
In a mouse model nuclear transfer embryo-derived embryonic stem cell lines (ntESCs) of various genetic backgrounds and donor cell types were compared with reference ESCs and analyzed comprehensively at molecular level as a second part of a larger study. Expression profiles of ntESCs established by different NT-methods (piezoelectric microinjection or zona-free) were indistinguishable. However, expression...
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