Article
Cord blood analysis for rapid prenatal confirmation of Hb Bart's disease using the Sebia Capillary electrophoresis system.
Hemoglobin - 1 Jan 2012
Liao Can, Zhou Jian-Ying, Xie Xing-Mei, Li Ru, Li Dong-Zhi
Abstract excerpt
Prenatal diagnosis of severe α-thalassemia (α-thal) diseases is usually performed by DNA analysis. To establish a simple and rapid method, we evaluated the reliability of cord blood hemoglobin (Hb) analysis using an automated capillary electrophoresis (CE) system. Our results demonstrated that analysis of fetal Hb using the Sebia CapillaryS 2 is an effective, accurate and simple alternative for prenatal diagnosis...
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