Article
Alterations in the gut microbiome of children with severe ulcerative colitis.
Inflammatory bowel diseases - 1 Oct 2012
Michail Sonia, Durbin Matthew, Turner Dan, Griffiths Anne M, Mack David R, Hyams Jeffrey, Leleiko Neal, Kenche Harshavardhan, Stolfi Adrienne, Wine Eytan
Abstract excerpt
BACKGROUND: Although the role of microbes in disease pathogenesis is well established, data describing the variability of the vast microbiome in children diagnosed with ulcerative colitis (UC) are lacking. This study characterizes the gut microbiome in hospitalized children with severe UC and determines the relationship between microbiota and response to steroid therapy. METHODS: Fecal samples were collected from...
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