Article
Coupling technique of random amplified polymorphic DNA and nanoelectrochemical sensor for mapping pancreatic cancer genetic fingerprint.
International journal of nanomedicine - 1 Jan 2011
Liu Qicai, Liu Ailin, Gao Feng, Weng Shaohuang, Zhong Guangxian, Liu Jingfeng, Lin Xinhua, Lin Jian-hua, Chen Xuhai
Abstract excerpt
OBJECTIVE: To review the feasibility of coupling the techniques of random amplified polymorphic DNA (RAPD) with carbon nanotube-based modified electrode for guanine/deoxyguanine triphosphate (dGTP) electrochemical sensing for mapping of the pancreatic cancer genetic fingerprint and screening of genetic alterations. METHODS: We developed a new method to study the electrochemical behavior of dGTP utilizing carbon...
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