Article
A common missense single nucleotide polymorphism in the E-selectin gene is significantly associated with essential hypertension in the Han population but only weakly associated in the Uygur population.
Hypertension research : official journal of the Japanese Society of Hypertension - 1 Apr 2012
Wang Zhong, Xu Yujun, Chen Shaoze, Wang Li, Ding Hu, Lu Guilin, Wang Daowen, Zhai Zhihong, Duan Juncang, Zhang Wangqiang
Abstract excerpt
Experimental and clinical observations suggest that E-selectin could have an important role in essential hypertension (EH), but the relationship between common E-selectin variants and EH has not been extensively studied in the Chinese population. In this study, we explored the association between two common variants in the E-selectin gene (rs5361A/C and rs5355C/T) and EH in the Uygur, Kazakh and Han populations...
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