Article
E-selectin gene polymorphisms are associated with essential hypertension: a case-control pilot study in a Chinese population.
BMC medical genetics - 27 Aug 2010
Wang Zuoguang, Liu Ya, Liu Jieling, Liu Kuo, Lou Yuqin, Wen Jie, Niu Qiuli, Wen Shaojun, Wu Zhaosu
Abstract excerpt
BACKGROUND: Genetic variation is thought to contribute to the etiology of hypertension, and E-selectin is a candidate essential hypertension-associated gene. This study thus sought to investigate possible genetic associations between the T1880C, C602A and T1559C polymorphisms of E-selectin and essential hypertension. METHODS: Hypertensive patients (n = 490) and healthy normotensive subjects (n = 495) were...
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