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Article

HLA-DRB1*010101 allele is closely associated with poor virological response to lamivudine therapy in patients with chronic hepatitis B.

Digestion - 1 Jan 2011

Jin Young-Joo, Shim Ju Hyun, Chung Young-Hwa, Kim Jeong A, Choi Jong Gi, Park Won Hyung, Lee Danbi, Kim Sung Eun, Lee Yoon Seon, Kim Sung Hoon, Yang Soo Hyun

Abstract excerpt

BACKGROUND/AIMS: We intended to evaluate the association between specific human leukocyte antigen (HLA)-DRB1 gene polymorphism and antiviral response to lamivudine (LAM) therapy in chronic hepatitis B (CHB) patients. METHODS: Six-digit HLA-DRB1 genotypes were determined using sequence-based typing in 334 CHB patients initially treated with LAM for at least 12 months. Antiviral response was evaluated every 3-6...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22156484
DOI: 10.1159/000333783

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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