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Article

Association of hypoxia inducible factor-1α polymorphisms with susceptibility to non-small-cell lung cancer.

Translational research : the journal of laboratory and clinical medicine - 1 Jan 2012

Kuo Wu-Hsien, Shih Chuen-Ming, Lin Chiao-Wen, Cheng Wei-Erh, Chen Shuo-Chueh, Chen Wei, Lee Yao-Ling

Abstract excerpt

Hypoxia-inducible factor-1α (HIF-1α) is a key regulator of cellular response to hypoxia and has been suggested to play an important role in tumorigenesis and metastasis. The aim of this study was to investigate the role of HIF-1α-1772 C/T (P582S) and -1790 G/A (A588T) polymorphisms in the susceptibility to and severity of non-small-cell lung cancer (NSCLC). Using a case-control study design and polymerase chain...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22153809
DOI: 10.1016/j.trsl.2011.09.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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