Article
Octanoylation of the lipoyl domains of the pyruvate dehydrogenase complex in a lipoyl-deficient strain of Escherichia coli.
Molecular microbiology - 1 Jun 1990
Ali S T, Moir A J, Ashton P R, Engel P C, Guest J R
Abstract excerpt
The overexpression of a subgene encoding a hybrid lipoyl domain of the dihydrolipoamide acetyltransferase component of the pyruvate dehydrogenase complex of Escherichia coli has previously been shown to result in the formation of lipoylated and unlipoylated products. Overexpression of the same subgene in a lipoic acid biosynthesis mutant growing under lipoate-deficient conditions has now been shown to produce...
Topics
- Amino Acid Sequence
- Caprylates
- Escherichia coli
- Molecular Sequence Data
- Mutation
- Plasmids
- Protein Processing, Post-Translational
- Pyruvate Dehydrogenase Complex
- Thioctic Acid