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Article

Critical role of LuxS in the virulence of Campylobacter jejuni in a guinea pig model of abortion.

Infection and immunity - 1 Feb 2012

Plummer Paul, Sahin Orhan, Burrough Eric, Sippy Rachel, Mou Kathy, Rabenold Jessica, Yaeger Mike, Zhang Qijing

Abstract excerpt

Previous studies on Campylobacter jejuni have demonstrated the role of LuxS in motility, cytolethal distending toxin production, agglutination, and intestinal colonization; however, its direct involvement in virulence has not been reported. In this study, we demonstrate a direct role of luxS in the virulence of C. jejuni in two different animal hosts. The IA3902 strain, a highly virulent sheep abortion strain...

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Identifiers

PMID: 22144479
DOI: 10.1128/IAI.05766-11
PMCID: PMC3264297

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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