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Article

Meta-analysis of 8q24 for seven cancers reveals a locus between NOV and ENPP2 associated with cancer development.

BMC medical genetics - 5 Dec 2011

Brisbin Abra G, Asmann Yan W, Song Honglin, Tsai Ya-Yu, Aakre Jeremiah A, Yang Ping, Jenkins Robert B, Pharoah Paul, Schumacher Fredrick, Conti David V, Duggan David J, Jenkins Mark, Hopper John, Gallinger Steven, Newcomb Polly, Casey Graham, Sellers Thomas A, Fridley Brooke L

Abstract excerpt

BACKGROUND: Human chromosomal region 8q24 contains several genes which could be functionally related to cancer, including the proto-oncogene c-MYC. However, the abundance of associations around 128 Mb on chromosome 8 could mask the appearance of a weaker, but important, association elsewhere on 8q24. METHODS: In this study, we completed a meta-analysis of results from nine genome-wide association studies for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22142333
DOI: 10.1186/1471-2350-12-156
PMCID: PMC3267702

Genes

ENPP2
MYC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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