Article
Functional characterization of a rare germline mutation in the gene encoding the cyclin-dependent kinase inhibitor p27Kip1 (CDKN1B) in a Spanish patient with multiple endocrine neoplasia-like phenotype.
European journal of endocrinology - 1 Mar 2012
Malanga Donatella, De Gisi Silvia, Riccardi Miriam, Scrima Marianna, De Marco Carmela, Robledo Mercedes, Viglietto Giuseppe
Abstract excerpt
OBJECTIVE: The aim of this study was to investigate the presence of germline mutations in the CDKN1B gene that encodes the cyclin-dependent kinase (Cdk) inhibitor p27 in multiple endocrine neoplasia 1 (MEN1)-like Spanish index patients. The CDKN1B gene has recently been identified as a tumor susc...
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