Article
Multiple testing in high-throughput sequence data: experiences from Group 8 of Genetic Analysis Workshop 17.
Genetic epidemiology - 1 Jan 2011
König Inke R, Nsengimana Jeremie, Papachristou Charalampos, Simonson Matthew A, Wang Kai, Weisburd Jason A
Abstract excerpt
The use of high-throughput sequence data in genetic epidemiology allows the investigation of common and rare variants in the entire genome, thus increasing the amount of information and the potential number of statistical tests performed within one study. As a consequence, the problem of multiple testing may become even more pressing than in previous studies. As an important challenge, the exact number of...
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