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Article

Genetically-determined hyperfunction of the S100B/RAGE axis is a risk factor for aspergillosis in stem cell transplant recipients.

PloS one - 1 Jan 2011

Cunha Cristina, Giovannini Gloria, Pierini Antonio, Bell Alain S, Sorci Guglielmo, Riuzzi Francesca, Donato Rosario, Rodrigues Fernando, Velardi Andrea, Aversa Franco, Romani Luigina, Carvalho Agostinho

Abstract excerpt

Invasive aspergillosis (IA) is a major threat to the successful outcome of hematopoietic stem cell transplantation (HSCT), although individual risk varies considerably. Recent evidence has established a pivotal role for a danger sensing mechanism implicating the S100B/receptor for advanced glycation end products (RAGE) axis in antifungal immunity. The association of selected genetic variants in the S100B/RAGE...

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Identifiers

PMID: 22114731
DOI: 10.1371/journal.pone.0027962
PMCID: PMC3219695

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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