Article
[Study on association between single nucleotide polymorphisms of MMP7, MMP8, MMP9 genes and development of gastric cancer and lymph node metastasis].
The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi - 25 Nov 2011
Kim Ji Hye, Pyun Jung A, Lee Kwang Jae, Cho Sung Won, Kwack Kyu Bum
Abstract excerpt
BACKGROUND/AIMS: Matrix metallopeptidase (MMP) is known to be involved in tumor invasion and metastasis of cancer. This study investigated the association of MMP7 rs11568818, MMP8 rs11225395, MMP9 rs17576 and rs2250889 with gastric cancer (GC) development and lymph node metastasis (LNM). METHODS: Samples were obtained from 326 chronic gastritis (CG) and 153 GC patients and genotyped by using the GoldenGate®...
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