Article
Wild-type Drosophila melanogaster as a model host to analyze nitrogen source dependent virulence of Candida albicans.
PloS one - 1 Jan 2011
Davis Monica M, Alvarez Francisco J, Ryman Kicki, Holm Åsa A, Ljungdahl Per O, Engström Ylva
Abstract excerpt
The fungal pathogen Candida albicans is a common cause of opportunistic infections in humans. We report that wild-type Drosophila melanogaster (OrR) flies are susceptible to virulent C. albicans infections and have established experimental conditions that enable OrR flies to serve as model hosts for studying C. albicans virulence. After injection into the thorax, wild-type C. albicans cells disseminate and invade...
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