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Article

Treatment limitations imposed by antiretroviral drug resistance mutations: implication for choices of first line regimens in resource-limited settings.

HIV medicine - 1 Mar 2012

Mtambo A, Chan K, Shen A, Lima V, Hogg R, Montaner J, Moore D

Abstract excerpt

BACKGROUND: Recent studies have suggested that failing nonnucleoside reverse transcriptase inhibitor (NNRTI)-based regimens may have greater potential to induce the development of resistance mutations, which may limit options for second-line therapy. METHODS: Antiretroviral therapy (ART)-naïve individuals aged ≥18 years who initiated triple combination ART between January 2000 and June 2006 in British Columbia,...

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PMID: 22107262
DOI: 10.1111/j.1468-1293.2011.00950.x

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GSS

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