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Article

Clinical and genetic characterization of frontorhiny: report of 3 novel cases and discussion of the surgical management.

Archives of facial plastic surgery - 1 Jan 2000

Pham Nguyen S, Rafii Amir, Liu Jia, Boyadjiev Simeon A, Tollefson Travis T

Abstract excerpt

OBJECTIVES: To (1) define the nasal, columellar, and lip deformities of 3 patients with characteristics consistent with frontorhiny; (2) illustrate the embryologic correlation of the oronasal findings to the development of the median nasal prominence; (3) report the clinical manifestation in 3 patients from 2 unrelated families; (4) report a novel Y214X mutation in ALX3 ; and (5) describe the surgical...

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Source

Identifiers

PMID: 22106187
DOI: 10.1001/archfacial.2011.684

Genes

ALX3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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