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Thrombocytopenias due to gray platelet syndrome or THC2 mutations.

Seminars in thrombosis and hemostasis - 1 Sept 2011

Di Paola Jorge, Johnson Jan

Abstract excerpt

Over the last two decades the genetic causes of several Mendelian platelet disorders have been elucidated, while the genetics of many other thrombocytopenic conditions are still unresolved. Among those are the gray platelet syndrome (GPS) and the thrombocytopenia linked to the THC2 locus on human chromosome 10p11-12. GPS is an α-granule defect associated with the development of myelofibrosis and mild to moderate...

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PMID: 22102272
DOI: 10.1055/s-0031-1291379

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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