Article
Substrate binding of a GH5 endoglucanase from the ruminal fungus Piromyces rhizinflata.
Acta crystallographica. Section F, Structural biology and crystallization communications - 1 Oct 2011
Tseng Chih Wen, Ko Tzu Ping, Guo Rey Ting, Huang Jian Wen, Wang Hao Ching, Huang Chun Hsiang, Cheng Ya Shan, Wang Andrew H J, Liu Je Ruei
Abstract excerpt
The endoglucanase EglA from Piromyces rhizinflata found in cattle stomach belongs to the GH5 family of glycoside hydrolases. The crystal structure of the catalytic domain of EglA shows the (β/α)(8)-barrel fold typical of GH5 enzymes. Adjacent to the active site of EglA, a loop containing a disulfide bond not found in other similar structures may participate in substrate binding. Because the active site was...
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