Nuclear factor-kappa B inhibitors; a patent review (2006 – 2010)

Abstract excerpt

INTRODUCTION: Nuclear factor (NF)-κB, as transcription factor, is linked to the expression of various genes and plays an essential role in immune and inflammatory responses. Abnormal NF-κB signaling results in human diseases, such as immune disorders, inflammation and various cancers. Therefore, regulation of NF-κB may treat or improve the symptoms in human disorders. AREAS COVERED: This review provides...

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