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Article

Effect of transmission reduction by insecticide-treated bednets (ITNs) on antimalarial drug resistance in western Kenya.

PloS one - 1 Jan 2011

Shah Monica, Kariuki Simon, Vanden Eng Jodi, Blackstock Anna J, Garner Kimberly, Gatei Wangeci, Gimnig John E, Lindblade Kim, Terlouw Dianne, ter Kuile Feiko, Hawley William A, Phillips-Howard Penelope, Nahlen Bernard, Walker Edward, Hamel Mary J, Slutsker Laurence, Shi Ya Ping

Abstract excerpt

Despite the clear public health benefit of insecticide-treated bednets (ITNs), the impact of malaria transmission-reduction by vector control on the spread of drug resistance is not well understood. In the present study, the effect of sustained transmission reduction by ITNs on the prevalence of Plasmodium falciparum gene mutations associated with resistance to the antimalarial drugs sulfadoxine-pyrimethamine...

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Identifiers

PMID: 22096496
DOI: 10.1371/journal.pone.0026746
PMCID: PMC3214025

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