Article
The role of mitochondria in the aging processes of yeast.
Sub-cellular biochemistry - 1 Jan 2012
Breitenbach Michael, Laun Peter, Dickinson J Richard, Klocker Andrea, Rinnerthaler Mark, Dawes Ian W, Aung-Htut May T, Breitenbach-Koller Lore, Caballero Antonio, Nyström Thomas, Büttner Sabrina, Eisenberg Tobias, Madeo Frank, Ralser Markus
Abstract excerpt
This chapter reviews the role of mitochondria and of mitochondrial metabolism in the aging processes of yeast and the existing evidence for the "mitochondrial theory of aging mitochondrial theory of aging ". Mitochondria are the major source of ATP in the eukaryotic cell but are also a major source of reactive oxygen species reactive oxygen species (ROS) and play an important role in the process of apoptosis and...
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