Article
Mutation of pfm affects the adherence of Pseudomonas aeruginosa to host cells and the quorum sensing system.
FEMS microbiology letters - 1 Nov 2011
Mou Rui, Bai Fang, Duan Qiaonan, Wang Xuehan, Xu Haijin, Bai Yanling, Zhang Xiuming, Jin Shouguang, Qiao Mingqiang
Abstract excerpt
The Pseudomonas aeruginosa quorum sensing (QS) system is controlled by the signal molecules acyl homoserine lactones (AHLs) that are synthesized from acyl enoyl-acyl carrier proteins (acyl-ACPs) provided by the fatty acid biosynthesis cycle. Pfm (PA2950), an enoyl-CoA reductase, has previously been shown to affect swimming mobility and fatty acid biosynthesis. In this report, we further show that pfm influences...
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