Article
Interplay between mutational and horizontally acquired resistance mechanisms and its association with carbapenem resistance amongst extensively drug-resistant Pseudomonas aeruginosa (XDR-PA).
International journal of antimicrobial agents - 1 Mar 2012
Shu Jwu-Ching, Chia Ju-Hsin, Siu Leung-Kei, Kuo An-Jing, Huang Shu-Huan, Su Lin-Hui, Wu Tsu-Lan
Abstract excerpt
Between 2003 and 2009, the prevalence of extensively drug-resistant Pseudomonas aeruginosa (XDR-PA) increased significantly in northern Taiwan from 1.0% to 2.1%. Molecular methods were used to investigate the genetic relatedness and carbapenem resistance mechanisms of a collection of 203 non-repetitive XDR-PA isolates available for study. Using pulsed-field gel electrophoresis (PFGE), 52 genotypes were observed;...
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