Article
Phenotypic pattern-based assay for dynamically monitoring host cellular responses to Salmonella infections.
PloS one - 1 Jan 2011
Mou Xiaozhou, Wan Shuying, Li Yifei, Zhang Shanshan, Sun Mingjiao, Liu Fanglong, Fu Huiying, Zhang Xue, Liu Haiying, Cao Qian, Ke Yuehai, Xiang Charlie
Abstract excerpt
The interaction between mammalian host cells and bacteria is a dynamic process, and the underlying pathologic mechanisms are poorly characterized. Limited information describing the host-bacterial interaction is based mainly on studies using label-based endpoint assays that detect changes in cell behavior at a given time point, yielding incomplete information. In this paper, a novel, label-free, real-time...
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