Article
Ilaprazole for the treatment of duodenal ulcer: a randomized, double-blind and controlled phase III trial.
Current medical research and opinion - 1 Jan 2012
Wang Ling, Zhou Liya, Hu Haitang, Lin Sanren, Xia Jielai
Abstract excerpt
OBJECTIVE: The new proton pump inhibitor (PPI), ilaprazole performed better at the dose of 10 mg/d relative to 5 or 20 mg/d in a previous phase II trial. A larger phase III trial was carried out to confirm the efficacy and safety of ilaprazole (10 mg/d) compared with omeprazole (20 mg/d) and provide some characteristics of the relationship between ilaprazole metabolism and CYP2C19 for later studies. RESEARCH...
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