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The evolution of menstruation: A new model for genetic assimilation

7 Nov 2011

Abstract excerpt

Why do humans menstruate while most mammals do not? Here, we present our answer to this long-debated question, arguing that (i) menstruation occurs as a mechanistic consequence of hormone-induced differentiation of the endometrium (referred to as spontaneous decidualization, or SD); (ii) SD evolved because of maternal-fetal conflict; and (iii) SD evolved by genetic assimilation of the decidualization reaction,...

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PMID: 22057551
DOI: 10.1002/bies.201100099

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