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"Targeted disruption of the epithelial-barrier by Helicobacter pylori"

1 Nov 2011

Abstract excerpt

Helicobacter pylori colonizes the human gastric epithelium and induces chronic gastritis, which can lead to gastric cancer. Through cell-cell contacts the gastric epithelium forms a barrier to protect underlying tissue from pathogenic bacteria; however, H. pylori have evolved numerous strategies to perturb the integrity of the gastric barrier. In this review, we summarize recent research into the mechanisms...

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PMID: 22044698
DOI: 10.1186/1478-811x-9-29

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