Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Derivation and Validation of a Simple Exercise-Based Algorithm for Prediction of Genetic Testing in Relatives of LQTS Probands

1 Nov 2011

Abstract excerpt

BACKGROUND: Genetic testing can diagnose long-QT syndrome (LQTS) in asymptomatic relatives of patients with an identified mutation; however, it is costly and subject to availability. The accuracy of a simple algorithm that incorporates resting and exercise ECG parameters for screening LQTS in asymptomatic relatives was evaluated, with genetic testing as the gold standard. METHODS AND RESULTS: Asymptomatic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiac electrophysiology and arrhythmias
Share to Cardiovascular Effects of Exercise
Share to Takotsubo Cardiomyopathy and Associated Phenomena

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22042885
DOI: 10.1161/circulationaha.111.028258

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Derivation and Validation of a Simple Exercise-Based Algorithm for Prediction of Genetic Testing in Relatives of LQTS ProbandsPMID 22042885Read ↗

Utility of the recovery electrocardiogram after exercise: a novel indicator for the diagnosis and genotyping of long QT syndrome?Semantic proximity Read ↗

End-recovery QTc: a useful metric for assessing genetic variants of unknown significance in long-QT syndrome.Semantic proximity Read ↗

Utility of treadmill testing in identification and genotype prediction in long-QT syndrome.Semantic proximity Read ↗

Abnormal repolarization dynamics revealed in exercise test in long QT syndrome mutation carriers with normal resting QT interval.Semantic proximity Read ↗

Corrected QT Interval-Polygenic Risk Score and Its Contribution to Type 1, Type 2, and Type 3 Long-QT Syndrome in Probands and Genotype-Positive Family Members.Semantic proximity Read ↗

Repolarization dynamics during exercise discriminate between LQT1 and LQT2 genotypes.Semantic proximity Read ↗

Utility of Provocative Testing in the Diagnosis and Genotyping of Congenital Long QT Syndrome: A Systematic Review and Meta-Analysis.Semantic proximity Read ↗

Do LQTS gene single nucleotide polymorphisms alter QTc intervals at rest and during exercise stress testing?Semantic proximity Read ↗

Treadmill exercise testing improves diagnostic accuracy in children with concealed congenital long QT syndrome.Semantic proximity Read ↗

Risk of syncope in family members who are genotype-negative for a family-associated long-QT syndrome mutation.Semantic proximity Read ↗

Sudden cardiac death in young athletes with long QT syndrome: the role of genetic testing and cardiovascular screening.Semantic proximity Read ↗

Differentiation between LQT1 and LQT2 patients and unaffected subjects using 24-hour electrocardiographic recordings.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.