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Interactions of Metal Ions with DNA, Its Constituents and Derivatives, which may be Relevant for Anticancer Research

1 Nov 2011

Abstract excerpt

In this review several types of interactions between metal ions and DNA are given, starting from basic binding to the use of metal complexes in cancer treatment and diagnostics. Metal cations help to neutralize the negative charge of DNA and thus enable the normal functions of DNA but many other interactions are also possible and are discussed in this paper. Various consequences of such interactions can be...

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PMID: 22039873
DOI: 10.2174/156802611798040787

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