Single gene disorders of the aortic wall.

Abstract excerpt

Genetic diseases that affect the vasculature primarily affect the aortic root and ascending aorta. These conditions lead to aortic root dilatation, which, if not treated, will result in dissection and death. Often, aortic disease is just one manifestation of a syndrome with diverse findings. Some of these diseases were described over 100 years ago based on physical manifestations, and their causative genes are...

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• Aorta
• Aortic Aneurysm, Thoracic
• Aortic Diseases
• Aortic Dissection
• Ehlers-Danlos Syndrome