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Article

Osteogenic differentiation of stem cells alters vitamin D receptor expression.

Stem cells and development - 1 Jul 2012

Olivares-Navarrete Rene, Sutha Ken, Hyzy Sharon L, Hutton Daphne L, Schwartz Zvi, McDevitt Todd, Boyan Barbara D

Abstract excerpt

Pluripotent and multipotent stem cells adopt an osteoblastic phenotype when cultured in environments that enhance their osteogenic potential. Embryonic stem cells differentiated as embryoid bodies (EBs) in osteogenic medium containing β-glycerophosphate exhibit increased expression of bone markers, indicating that cells are osteoblastic. Interestingly, 1α,25-dihydroxyvitaminD3 (1,25D) enhances the osteogenic...

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Identifiers

PMID: 22034957
DOI: 10.1089/scd.2011.0411
PMCID: PMC3376455

Genes

VDR
PDIA3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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