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Article

Role of noncoding RNA ANRIL in genesis of plexiform neurofibromas in neurofibromatosis type 1.

Journal of the National Cancer Institute - 16 Nov 2011

Pasmant Eric, Sabbagh Audrey, Masliah-Planchon Julien, Ortonne Nicolas, Laurendeau Ingrid, Melin Lucie, Ferkal Salah, Hernandez Lucie, Leroy Karen, Valeyrie-Allanore Laurence, Parfait Béatrice, Vidaud Dominique, Bièche Ivan, Lantieri Laurent, Wolkenstein Pierre, Vidaud Michel

Abstract excerpt

BACKGROUND: Neurofibromatosis type 1 (NF1) is a tumor predisposition syndrome with a worldwide birth incidence of one in 2500. Genetic factors unrelated to the NF1 locus are thought to influence the number of plexiform neurofibromas (PNFs) in patients with NF1, but no factors have been identified to date. METHODS: We used high-resolution array comparative genomic hybridization of tissue from 22 PNFs obtained from...

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PMID: 22034633
DOI: 10.1093/jnci/djr416

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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