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Efficient Generation of iPS Cells from Skeletal Muscle Stem Cells

18 Oct 2011

Abstract excerpt

Reprogramming of somatic cells into inducible pluripotent stem cells generally occurs at low efficiency, although what limits reprogramming of particular cell types is poorly understood. Recent data suggest that the differentiation status of the cell targeted for reprogramming may influence its susceptibility to reprogramming as well as the differentiation potential of the induced pluripotent stem (iPS) cells...

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PMID: 22028872
DOI: 10.1371/journal.pone.0026406

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