Article
Chondrolectin is a novel diagnostic biomarker and a therapeutic target for lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Dec 2011
Masuda Ken, Takano Atsushi, Oshita Hideto, Akiyama Hirohiko, Tsuchiya Eiju, Kohno Nobuoki, Nakamura Yusuke, Daigo Yataro
Abstract excerpt
PURPOSE: This study aims to identify molecules that might be useful as diagnostic/prognostic biomarkers and as targets for the development of new molecular therapies for lung cancer. EXPERIMENTAL DESIGN: We screened for genes that were highly transactivated in a large proportion of 120 lung cancers by means of a cDNA microarray representing 27,648 genes and found chondrolectin (CHODL) as a candidate. Tumor tissue...
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