[Significance of the JAK2V617F mutation in patients with chronic myeloproliferative neoplasia].

doi:10.1556/OH.2011.29226

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Article

[Significance of the JAK2V617F mutation in patients with chronic myeloproliferative neoplasia].

Orvosi hetilap - 6 Nov 2011

Iványi János László, Marton Eva, Plander Márk

Abstract excerpt

UNLABELLED: In Philadelphia chromosome-negative chronic myeloproliferative neoplasia, i.e. polycythemia vera, essential thrombocythemia and primary idiopathic myelofibrosis enhanced risk of thrombosis could be connected with Janus kinase 2 gene mutation occurring in various frequency in these diseases (JAK2V617F). Since 2002 the presence of JAK2 mutation in chronic myeloproliferative neoplasia has been regularly...

Topics

Adult
Aged
Bone Marrow Neoplasms
Chronic Disease
Female
Humans
Janus Kinase 2
Male
Middle Aged
Mutation
Myeloproliferative Disorders
Phenylalanine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polycythemia Vera

Polymerase Chain Reaction

Predictive Value of Tests

Primary Myelofibrosis

Retrospective Studies

Signal Transduction

Source

Open in PubMed

Identifiers

PMID: 22011365
DOI: 10.1556/OH.2011.29226

Genes

JAK2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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[Significance of the JAK2V617F mutation in patients with chronic myeloproliferative neoplasia].PMID 22011365Read ↗

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[Essential thrombocythemia. Contribution of the V617F JAK2 mutation to the pathophysiology, diagnosis and outcome].Semantic proximity Read ↗

Clinical significance of V617F mutation of the JAK2 gene in patients with chronic myeloproliferative disorders.Semantic proximity Read ↗

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JAK2 mutation-related disease and thrombosis.Semantic proximity Read ↗

[Role of the activating mutation Val617Phe of Janus kinase 2 gene in myeloproliferative diseases and significance of its detection].Semantic proximity Read ↗

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[Novel method in diagnosis of chronic myeloproliferative disorders--detection of JAK2 mutation].Semantic proximity Read ↗

[New molecular markers within the chronic myeloproliferative disorders. II: the JAK2 mutation].Semantic proximity Read ↗

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