Article
Clinical significance of V617F mutation of the JAK2 gene in patients with chronic myeloproliferative disorders.
Hematology (Amsterdam, Netherlands) - 1 Dec 2009
Basquiera Ana L, Soria Néstor W, Ryser Ricardo, Salguero Miriam, Moiraghi Beatriz, Sackmann Federico, Sturich Ana G, Borello Adriana, Berretta Adriana, Bonafé Miriam, Barral José Moreno, Palazzo Emilio D, García Juan J
Abstract excerpt
OBJECTIVE: To determine the prevalence of JAK2 V617F mutation and its clinical correlation in patients with chronic myeloproliferative disorders (CMD): polycythemia vera (PV), essential thrombocythemia (ET) and idiopathic myelofibrosis (IMF). MATERIALS AND METHODS: Detection of JAK2 V617F mutation by allele specific-PCR. RESULTS: One hundred and three patients with CMD were included in the study. JAK2 V617F...
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