Epoxides: comparison of the induction of SOS repair in Escherichia coli PQ37 and the bacterial mutagenicity in the Ames test.

doi:10.1016/0027-5107(90)90027-2

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Article

Epoxides: comparison of the induction of SOS repair in Escherichia coli PQ37 and the bacterial mutagenicity in the Ames test.

Mutation research - 1 Aug 1990

von der Hude W, Seelbach A, Basler A

Abstract excerpt

The genotoxicity of 51 epoxides is studied with the SOS-Chromotest using Escherichia coli PQ37 as tester strain. The results obtained with this test system are compared with results of the Ames test. Out of 51 epoxides, 39 are shown to be mutagenic in Salmonella typhimurium whereas only 27 mutage...

Topics

DNA Repair
Epoxy Compounds
Escherichia coli
Ethers, Cyclic
Mutagenicity Tests
Mutation
SOS Response, Genetics

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