Article
Evidence for sequential action of Rab5 and Rab7 GTPases in prevacuolar organelle partitioning.
Traffic (Copenhagen, Denmark) - 1 Feb 2012
Bottanelli Francesca, Gershlick David C, Denecke Jürgen
Abstract excerpt
GTPases of the Rab5 and Rab7 families were shown to control vacuolar sorting but their specific subcellular localization is controversial in plants. Here, we show that both the canonical as well as the plant-specific Rab5 reside at the newly discovered 'late prevacuolar compartment' (LPVC) while Rab7 partitions to the vacuolar membrane when expressed at low levels. Higher expression levels of wild-type Rab5...
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