AUC-RF: a new strategy for genomic profiling with random forest.

Abstract excerpt

OBJECTIVE: Genomic profiling, the use of genetic variants at multiple loci simultaneously for the prediction of disease risk, requires the selection of a set of genetic variants that best predicts disease status. The goal of this work was to provide a new selection algorithm for genomic profiling. METHODS: We propose a new algorithm for genomic profiling based on optimizing the area under the receiver operating...

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