Article
Altered distribution of mucosal NK cells during HIV infection.
Mucosal immunology - 1 Jan 2012
Sips M, Sciaranghella G, Diefenbach T, Dugast A-S, Berger C T, Liu Q, Kwon D, Ghebremichael M, Estes J D, Carrington M, Martin J N, Deeks S G, Hunt P W, Alter G
Abstract excerpt
The human gut mucosa is a major site of human immunodeficiency virus (HIV) infection and infection-associated pathogenesis. Increasing evidence shows that natural killer (NK) cells have an important role in control of HIV infection, but the mechanism(s) by which they mediate antiviral activity in the gut is unclear. Here, we show that two distinct subsets of NK cells exist in the gut, one localized to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.