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Article

Transplantation of mature adipocyte-derived dedifferentiated fat (DFAT) cells improves urethral sphincter contractility in a rat model.

International journal of urology : official journal of the Japanese Urological Association - 1 Dec 2011

Obinata Daisuke, Matsumoto Taro, Ikado Yuichiro, Sakuma Takahiro, Kano Koichiro, Fukuda Noboru, Yamaguchi Kenya, Mugishima Hideo, Takahashi Satoru

Abstract excerpt

OBJECTIVES: To examine the effects of mature adipocyte-derived dedifferentiated fat (DFAT) cell transplantation on urethral tissue regeneration and sphincter function. METHODS: Sixteen female Sprague-Dawley rats underwent vaginal distension (VD) for 3 h. Subsequently, green fluorescence protein (GFP)-labeled DFAT cells (1×10(6) in 20 µL saline, DFAT group, n=8) or saline (20 µL, control group, n=8) were injected...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 21991997
DOI: 10.1111/j.1442-2042.2011.02865.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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