Article
Ancient ancestry of KFDV and AHFV revealed by complete genome analyses of viruses isolated from ticks and mammalian hosts.
PLoS neglected tropical diseases - 1 Oct 2011
Dodd Kimberly A, Bird Brian H, Khristova Marina L, Albariño César G, Carroll Serena A, Comer James A, Erickson Bobbie R, Rollin Pierre E, Nichol Stuart T
Abstract excerpt
BACKGROUND: Alkhurma hemorrhagic fever virus (AHFV) and Kyasanur forest disease virus (KFDV) cause significant human disease and mortality in Saudi Arabia and India, respectively. Despite their distinct geographic ranges, AHFV and KFDV share a remarkably high sequence identity. Given its emergence decades after KFDV, AHFV has since been considered a variant of KFDV and thought to have arisen from an introduction...
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