Article
Therapeutics of Ebola hemorrhagic fever: whole-genome transcriptional analysis of successful disease mitigation.
The Journal of infectious diseases - 1 Nov 2011
Yen Judy Y, Garamszegi Sara, Geisbert Joan B, Rubins Kathleen H, Geisbert Thomas W, Honko Anna, Xia Yu, Connor John H, Hensley Lisa E
Abstract excerpt
The mechanisms of Ebola (EBOV) pathogenesis are only partially understood, but the dysregulation of normal host immune responses (including destruction of lymphocytes, increases in circulating cytokine levels, and development of coagulation abnormalities) is thought to play a major role. Accumula...
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