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Article

T-cell lymphoblastic lymphoma shows differences and similarities with T-cell acute lymphoblastic leukemia by genomic and gene expression analyses.

Genes, chromosomes & cancer - 1 Dec 2011

Basso Katia, Mussolin Lara, Lettieri Antonella, Brahmachary Manisha, Lim Wei Keat, Califano Andrea, Basso Giuseppe, Biondi Andrea, Cazzaniga Giovanni, Rosolen Angelo

Abstract excerpt

T-cell acute lymphoblastic leukemia (T-ALL) and lymphoma (T-LBL) share common morphological and immunophenotypic features and are treated with similar therapeutic approaches. Nonetheless, they show distinct clinical presentations, suggesting that they may represent two different biological entities. To investigate the genetic characteristics of T-LBL and T-ALL, we used genomic and transcriptional profiling...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Leukemic

Share to Genome-Wide Association Study

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Share to Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

Share to Receptor, Notch1

Source

Identifiers

PMID: 21987448
DOI: 10.1002/gcc.20924

Genes

NOTCH1

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